2023, Cilt 10, Sayı 1, Sayfa(lar) 024-041
Investigation of Interventional Studies on COVID-19 in Turkey: A Systematic Review
Eda ÜNAL1, Ayşe ARIKAN DÖNMEZ2, Fatma İlknur ÇINAR3
1Arş.Gör., Aksaray Üniversitesi, Sağlık Bilimleri Fakültesi, Hemşirelik Bölümü, Aksaray, Türkiye
2Dr.Öğr.Üyesi, Hacettepe Üniversitesi, Hemşirelik Fakültesi, Ankara, Türkiye
3Prof.Dr., Sağlık Bilimleri Üniversitesi, Gülhane Hemşirelik Fakültesi, Ankara, Türkiye
Keywords: COVID-19, non-pharmacological treatment, pharmacological treatment, systematic review, Turkey

Aim: This study aims to systematically review the interventional studies from Turkey published in national and international databases for the treatment and management of COVID-19.

Material and Methods: The studies conducted between January-2020 and August-2021 were searched through PubMed, Cochrane, CINAHL, EBSCHO, Web of Science, Google Scholar, Turkey Citation Index, ULAKBİM, and COVID-19 Turkey Web Portal. Fourteen studies meeting the criteria were included.

Results: The studies were conducted with randomized controlled (n=6), clinical trial (n=1), interventional double-controlled trial (n=1), and quasi-experimental study design (n=5). One is a randomized, prospective crossover, model simulation study. The evaluated studies include non-pharmacological (n=8) and pharmacological (n=6) approaches. Tele-rehabilitation or online methods were used in all non-pharmacological studies. Six studies aimed at reducing the stress, depression, and anxiety levels of individuals. Pharmacological studies were (n=6) aimed at evaluating the effectiveness of different treatment modalities. The result shows that interventions in non-pharmacological studies are highly effective, and treatment methods applied in pharmacological studies also have a positive effect.

Conclusion: This review will contribute to the literature by shedding light on future research. Moreover, there is a need for more comprehensive studies on the diagnosis, treatment, symptoms, effects, and management of COVID-19, including children and older people at risk.