Aim: The aim of this research is to examine the relationship between health promotion and meaning in life in adolescents.

Material and Methods: This research has a correlation design. It was conducted with adolescents studying at a public high school within the provincial borders of Usak between 15 December 2021 and 15 January 2022. The sample consisted of 505 adolescents. In the research, Questionnaire Form including socio-demographic characteristics, Adolescent Health Promotion Scale, and Meaning in Life High School Form were used.

Results: In the research, it was determined that adolescents got average scores from health promotion and meaning in life scales. In addition, strong positive and significant relationships were determined between health promotion and its sub-dimensions and the existence of meaning in life and the search for meaning. The health promotion scale score explained the variation in the existence of meaning in life scale score by 31%, and the variation in the search for meaning in life scale score by 30%.

Conclusion: It has been determined that the existence of meaning in life and the search for meaning in the adolescent's health promotion attitudes are significantly predicted. It is recommended to promote and maintain the health of adolescents in raising well-to-do adults in the future.