2017, Cilt 4, Sayı 1, Sayfa(lar) 073-092
Randomized Controlled Trials
Belgin AKIN1 , Deniz KOÇOĞLU2
1Selçuk Üniversitesi, Sağlık Bilimleri Fakültesi, Hemşirelik Bölümü, Halk Sağlığı Hemşireliği Anabilim Dalı, Konya
Keywords: Bias, causality, external validity, internal validity, randomized controlled trials

This review aims to explain the basic concepts and approaches related to randomized controlled trials, which is an important type of research with the development of viewpoint of evidence -based care. The success and quality of randomized controlled trials hinge upon observing the actual effect of the applied intervention on the emergence of the measured result. Establishing this cause-effect relation can be possible if randomized controlled trials are conducted within a protocol, use random assignment, avoid biase, ensure internal and external validity, use blind techniques and appropriate statistical evaluations. This review includes the mistakes made in these stages and the precaution to be taken.